Description
CATAG created this document to facilitate and support the translation of best available evidence into practice regarding the potential use of andexanet alfa for adult patients receiving a direct factor Xa inhibitor (apixaban or rivaroxaban) presenting with severe and life-threatening bleeds. The document provides consensus statements based on the current available evidence for andexanet alfa as of May 2024.
CATAG developed this document, based on the review of current literature and international cost-effectiveness reviews from Canada, UK and Scotland. An expert advisory group (EAG) was convened to review the evidence, agree on consensus statements, review drafts and feedback and approve the final position statement.
This document will assist good governance and decision-making for health service organisations, Medicines and Therapeutics Committees and health professionals. It can be used in conjunction with formulary decisions and recommendations.